1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. Endothelial cell CD Proteins
  4. CD201/Activated Protein C Receptor
  5. EPCR 蛋白, Mouse (HEK293, hFc)

EPCR 蛋白, Mouse (HEK293, hFc)

目录号: HY-P75246
产品使用指南

EPCR 蛋白在蛋白 C 通路中至关重要,通过凝血酶-血栓调节蛋白复合物结合并增强活化蛋白 C 的活化来调节血液凝固,确保有效控制止血。EPCR 蛋白, Mouse (HEK293, hFc) 是重组的 EPCR 蛋白,由 HEK293 表达,带有 C-hFc 标签。EPCR 蛋白, Mouse (HEK293, hFc) 全长 214 个氨基酸,分子量为 65-75 kDa。

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描述

EPCR Protein, crucial in the protein C pathway, regulates blood coagulation by binding and enhancing the activation of activated protein C through the thrombin-thrombomodulin complex, ensuring effective control of hemostasis. EPCR Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived EPCR protein, expressed by HEK293, with C-hFc labeled tag. The total length of EPCR Protein, Mouse (HEK293, hFc) is 214 a.a., with molecular weight of 65-75 kDa.

研究背景

EPCR 蛋白在调节凝血的蛋白 C 途径中起着至关重要的作用。它具有结合活化蛋白 C 的能力,并通过凝血酶-血栓调节蛋白复合物增强其活化作用。这种相互作用对于控制血液凝固和维持适当的止血至关重要。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q64695 (M1-S214)

基因 ID

19124  [NCBI]

蛋白结构
N-term
EPCR (M1-S214)
Accession # Q64695
hFc
C-term
同用名
Endothelial Protein C Receptor; CD201; PROCR; EPCR
分子量

65-75 kDa

纯度

Greater than 85% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
EPCR Protein, Mouse (HEK293, hFc)
目录号:
HY-P75246
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