FOLR1 蛋白, Rat (HEK293, Fc)

The FOLR1 protein is a member of the folate receptor family. Folate receptors are cell surface proteins that bind folate (vitamin B9) and transport it into cells. FOLR1 Protein, Rat (HEK293, Fc) is the recombinant rat-derived FOLR1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of FOLR1 Protein, Rat (HEK293, Fc) is 212 a.a., with molecular weight of ~50.9 kDa.

FOLR1 蛋白是叶酸受体家族的成员。叶酸受体是细胞表面蛋白，可结合叶酸（维生素 B9）并将其转运到细胞中。FOLR1广泛表达于多种组织，包括胎盘、肾、肺和肠。它通过介导细胞对叶酸的摄取在叶酸代谢中发挥至关重要的作用。FOLR1 在怀孕期间尤其重要，因为它促进叶酸穿过胎盘的运输以支持胎儿发育。除了在叶酸转运中的作用外，FOLR1 还参与其他细胞过程，包括细胞粘附、迁移和信号传导。它也被作为癌症治疗的潜在靶点进行研究，因为 FOLR1 表达在几种类型的癌细胞中经常上调，使其成为靶向药物递送的有希望的候选者。

Rat

HEK293

C-hFc

G3V8M6/NP_598211.1 (A20-M231)

171049  [NCBI]

AQSRATRARTELLNVCMDAKHHKEKPGPEDKLHDQCSPWKTNACCSTNTSQEDTKDISYLYRFNWNHCGTMTPECKRHFIQDTCLYECSPNLGPWIQQVDQSWRKERILDVPLCKEDCVLWWEDCKSSFTCKSNWLKGWNWTSGHNECPVGASCHPFTFYFPTPAVLCEKIWSHSYKLSNYSRGSGRCIQMWFDPAQGNPNEEVARFYAEVM

Approximately 50.9 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.