GIP 蛋白, Human (HEK293, hFc, solution)

The GIP protein is a member of the glucagon superfamily, an important incretin hormone that stimulates pancreatic beta cells to secrete insulin in response to food intake. Through its G protein-coupled receptor, it activates adenylyl cyclase and other signal transduction pathways. GIP Protein, Human (HEK293, hFc, solution) is the recombinant human-derived GIP protein, expressed by HEK293 , with C-hFc labeled tag. The total length of GIP Protein, Human (HEK293, hFc, solution) is 72 a.a., with molecular weight of ~38.77 kDa.

GIP 蛋白属于胰高血糖素超家族，是一种对葡萄糖稳态至关重要的肠促胰岛素激素。它的重要性在于它是胰腺β细胞响应食物摄入和营养吸收而分泌胰岛素的有效刺激剂。这种刺激是通过激活其 G 蛋白偶联受体、触发腺苷酸环化酶和其他信号转导途径而发生的。虽然 GIP 是一种相对较差的胃酸分泌抑制剂，但其在胰岛素调节中的主要作用使其成为代谢过程中的关键参与者。该基因表现出偏向表达，在十二指肠 (RPKM 96.0) 和小肠 (RPKM 33.9) 中检测到显着水平，强调其参与胃肠道内的消化和代谢功能。

Data is not available.

Human

HEK293

C-hFc

NP_004114.1 (E22-Q93)

2695  [NCBI]

EKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ

Approximately 38.77 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.