glycoprotein E/gE 蛋白, HHV-3 (Cell-Free, His)

Glycoprotein E/gE proteins bind to the host cell entry receptor IDE. glycoprotein E/gE Protein, HHV-3 (Cell-Free, His) is the recombinant Virus-derived glycoprotein E/gE protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of glycoprotein E/gE Protein, HHV-3 (Cell-Free, His) is 593 a.a., with molecular weight of 68.4 kDa.

包膜糖蛋白 E (gE) 通过与潜在的宿主细胞进入受体 IDE 结合，在病毒生命周期中发挥关键作用。gE/gI 异二聚体在上皮细胞中尤其重要，对于病毒在细胞间的有效传播至关重要，有助于将新生病毒体分选到细胞连接处。一旦位于这些连接处，病毒就会通过与在这些部位积累的细胞受体相互作用而快速传播到相邻细胞。此外，gE/gI 与极化细胞的基底外侧扩散有关。在神经元细胞中，gE/gI 异二聚体在感染在整个宿主神经系统中的顺行传播中发挥着至关重要的作用。这种异二聚体与 US9 合作，参与病毒结构成分向轴突尖端的分类和运输，有助于精心策划的感染进展。

Virus

E. coli Cell-free

N-10*His

Q9J3M8 (S31-R623)

/

SVLRYDDFHIDEDKLDTNSVYEPYYHSDHAESSWVNRGESSRKAYDHNSPYIWPRNDYDGFLENAHEHHGVYNQGRGIDSGERLMQPTQMSAQEDLGDDTGIHVIPTLNGDDRHKIVNVDQRQYGDVFKGDLNPKPQGQRLIEVSVEENHPFTLRAPIQRIYGVRYTETWSFLPSLTCTGDAAPAIQHICLKHTTCFQDVVVDVDCAENTKEDQLAEISYRFQGKKEADQPWIVVNTSTLFDELELDPPEIEPGVLKVLRTEKQYLGVYIWNMRGSDGTSTYATFLVTWKGDEKTRNPTPAVTPQPRGAEFHMWNYHSHVFSVGDTFSLAMHLQYKIHEAPFDLLLEWLYVPIDPTCQPMRLYSTCLYHPNAPQCLSHMNSGCTFTSPHLAQRVASTVYQNCEHADNYTAYCLGISHMEPSFGLILHDGGTTLKFVDTPESLSGLYVFVVYFNGHVEAVAYTVVSTVDHFVNAIEERGFPPTAGQPPATTKPKEITPVNPGTSPLLRYAAWTGGLAAVVLLCLVIFLICTAKRMRVKAYRVDKSPYNQSMYYAGLPVDDFEDSESTDTEEEFGNAIGGSHGGSSYTVYIDKTR

68.4 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.