1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens
  3. CSF & Receptors Stem Cell CD Proteins Dendritic Cell CD Proteins Endothelial cell CD Proteins
  4. IL-3R alpha/CD123
  5. IL-3R alpha/CD123 蛋白, Canine (299a.a, HEK293, His)

IL-3R alpha/CD123 蛋白, Canine (299a.a, HEK293, His)

目录号: HY-P77008
产品使用指南

IL-3R α/CD123蛋白是I型细胞因子受体家族的重要成员,介导细胞对多种细胞因子的反应,强调其在造血和免疫调节中的关键作用。IL-3R alpha/CD123 蛋白, Canine (299a.a, HEK293, His) 是重组的 IL-3R α/CD123 蛋白,由 HEK293 表达,带有 C-His 标签。IL-3R alpha/CD123 蛋白, Canine (299a.a, HEK293, His) 全长 299 个氨基酸,分子量约为 ~44 kDa。

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     可免费申领三个不同产品的试用装。

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描述

IL-3R α/CD123 protein is an important member of the type I cytokine receptor family and mediates cellular responses to a variety of cytokines, emphasizing its key role in hematopoiesis and immune regulation. IL-3R alpha/CD123 Protein, Canine (299a.a, HEK293, His) is the recombinant canine-derived IL-3R alpha/CD123 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-3R alpha/CD123 Protein, Canine (299a.a, HEK293, His) is 299 a.a., with molecular weight of ~44 kDa.

研究背景

IL-3R α/CD123 蛋白是 I 型细胞因子受体家族的重要成员,特别归类于 5 型亚家族,强调其在介导细胞对各种细胞因子的反应中的关键作用。作为该受体家族的一部分,IL-3R α/CD123 可能与相关受体具有保守的结构和功能特征,强调了其参与特定 I 型细胞因子信号的转导。I 型细胞因子受体家族的分类强调了其在更广泛的细胞信号传导背景下的特定名称,从而深入了解其对造血和免疫调节的独特贡献。IL-3R α/CD123 的研究有助于我们了解其在生理过程中的作用,并为造血障碍和免疫失调相关疾病的治疗干预提供了潜在的应用。对 IL-3R α/CD123 作用的进一步探索有望增强我们对其对正常细胞功能和病理状况的贡献的了解。

种属

Canine

表达系统

HEK293

标签

C-His

蛋白编号

XP_851626 (M1-R299)

基因 ID

609293  [NCBI]

蛋白结构
N-term
IL-3Rα (M1-R299)
Accession # XP_851626
His
C-term
同用名
Interleukin-3 receptor subunit alpha; IL-3R-alpha; IL-3RA; CD123
分子量

Approximately 44 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IL-3R alpha/CD123 Protein, Canine (299a.a, HEK293, His)
目录号:
HY-P77008
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