ITIH5 蛋白, Human (His-SUMO)

The ITIH5 protein was identified as a potential tumor suppressor, indicating its critical role in controlling tumorigenesis. As a tumor suppressor, ITIH5 is expected to counteract uncontrolled cell growth and inhibit or regulate key pathways in tumor development. ITIH5 Protein, Human (His-SUMO) is the recombinant human-derived ITIH5 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of ITIH5 Protein, Human (His-SUMO) is 127 a.a., with molecular weight of ~33 kDa.

ITIH5 蛋白作为一种潜在的肿瘤抑制因子出现，表明在调节肿瘤发生中发挥着至关重要的作用。其作为肿瘤抑制因子的指定意味着具有抵消癌细胞不受控制的细胞生长特征的能力。通过抑制或调节肿瘤发展中涉及的关键途径，ITIH5可能有助于维持正常细胞功能和预防恶性转化。ITIH5 作为假定的肿瘤抑制因子的特征强调了它在复杂的细胞调节机制网络中的重要性，需要进一步研究其具体的作用机制和在癌症管理中的潜在治疗意义。

Human

E. coli

N-SUMO;N-6*His

Q86UX2 (35V-161E)

80760  [NCBI]

VPRQVRLLQRLKTKPLMTEFSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITEREKKSGDRVKEKRNKTTEENGEKGTEIFRASAVIPSKDKAAFFLSYEE

Approximately 33 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.