2. 重组蛋白
  3. Receptor Proteins
  4. Pattern Recognition Receptors
  5. C-type Lectin Receptors
  6. Killer Cell Lectin Like Receptor G2 (KLRG2)
  7. KLRG2 蛋白, Human (P.pastoris, His)

KLRG2 蛋白, Human (P.pastoris, His)

目录号: HY-P71749
产品使用指南

KLRG2 蛋白, Human (P.pastoris, His) 是杀伤细胞凝集素样受体 (KLR) 家族成员之一，是一组优先在 NK 细胞中表达的跨膜蛋白。基因 KLRG2 的遗传变异可能影响诊断时的 Gleason 评分，从而影响前列腺癌的侵袭性。KLRG2 蛋白, Human (P.pastoris, His) 是重组的 KLRG2 蛋白，由 P. pastoris 表达，带有 N-His 标签。KLRG2 蛋白, Human (P.pastoris, His) 全长 409 个氨基酸，分子量约为 ~44.9 kDa。

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描述

KLRG2 Protein is a member of the killer cell lectin-like receptor (KLR) family, is a group of transmembrane proteins preferentially expressed in NK cells. Genetic variations in the gene KLRG2 may affect the Gleason score at diagnosis and thus the aggressiveness of prostate cancer. KLRG2 Protein, Human (P.pastoris, His) is the recombinant human-derived KLRG2 protein, expressed by P. pastoris , with N-His labeled tag. The total length of KLRG2 Protein, Human (P.pastoris, His) is 409 a.a., with molecular weight of ~44.9 kDa.
研究背景

KLRG2 是杀伤细胞凝集素样受体 (KLR) 家族成员之一，是一组优先在 NK 细胞中表达的跨膜蛋白。家族中另一个成员 KLRG1 是一种淋巴细胞共抑制或免疫检查点受体，主要表达于晚分化效应和效应记忆 CD8+ T 和 NK 细胞。基因 KLRG2 的遗传变异可能影响诊断时的 Gleason 评分，从而影响前列腺癌的侵袭性。
种属

Human
表达系统

P. pastoris
标签

N-His
蛋白编号

A4D1S0 (1M-409Q)
基因 ID
蛋白结构
N-term
His
KLRG2 (1M-409Q)
Accession # A4D1S0
C-term
同用名
KLRG2; CLEC15B; Killer cell lectin-like receptor subfamily G member 2; C-type lectin domain family 15 member B
氨基酸序列

MEESWEAAPGGQAGAELPMEPVGSLVPTLEQPQVPAKVRQPEGPESSPSPAGAVEKAAGAGLEPSSKKKPPSPRPGSPRVPPLSLGYGVCPEPPSPGPALVKLPRNGEAPGAEPAPSAWAPMELQVDVRVKPVGAAGGSSTPSPRPSTRFLKVPVPESPAFSRHADPAHQLLLRAPSQGGTWGRRSPLAAARTESGCDAEGRASPAEGSAGSPGSPTCCRCKELGLEKEDAALLPRAGLDGDEKLPRAVTLTGLPMYVKSLYWALAFMAVLLAVSGVVIVVLASRAGARCQQCPPGWVLSEEHCYYFSAEAQAWEASQAFCSAYHATLPLLSHTQDFLGRYPVSRHSWVGAWRGPQGWHWIDEAPLPPQLLPEDGEDNLDINCGALEEGTLVAANCSTPRPWVCAKGTQ

分子量

Approximately 44.9 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

KLRG2 Protein, Human (P.pastoris, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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