NECAP2 蛋白, Human (His)

NECAP2 protein plays a pivotal role in endocytosis, interacting with adapter protein complexes AP-1 and AP-2, specifically with AP1G1 and AP2A1. Additionally, it connects with GAE domain proteins GGA1, GGA2, and GGA3, participating in a network of interactions that orchestrate endocytic events. NECAP2 emerges as a key regulator in cellular processes associated with membrane trafficking and vesicular transport. NECAP2 Protein, Human (His) is the recombinant human-derived NECAP2 protein, expressed by E. coli , with N-6*His, C-6*His labeled tag. The total length of NECAP2 Protein, Human (His) is 263 a.a., with molecular weight of ~35.0 kDa.

NECAP2 蛋白在内吞作用的复杂过程中发挥着关键作用，它与接头蛋白复合物 AP-1 和 AP-2 的关键成分相互作用，特别是与 AP1G1 和 AP2A1 相互作用。此外，NECAP2 与 GAE 结构域蛋白 GGA1、GGA2 和 GGA3 建立连接，揭示其参与分子相互作用网络，从而有助于协调内吞事件。通过这些关联，NECAP2 成为调节与膜运输和囊泡运输相关的细胞过程的关键参与者。

Human

E. coli

N-6*His;C-6*His

Q9NVZ3 (M1-F263)

55707  [NCBI]

MEESGYESVLCVKPDVHVYRIPPRATNRGYRAAEWQLDQPSWSGRLRITAKGQMAYIKLEDRTSGELFAQAPVDQFPGTAVESVTDSSRYFVIRIEDGNGRRAFIGIGFGDRGDAFDFNVALQDHFKWVKQQCEFAKQAQNPDQGPKLDLGFKEGQTIKLNIANMKKKEGAAGNPRVRPASTGGLSLLPPPPGGKTSTLIPPPGEQLAVGGSLVQPAVAPSSGGAPVPWPQPNPATADIWGDFTKSTGSTSSQTQPGTGWVQF

Approximately 35.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.