NOX1 蛋白, Human (Cell-Free, His)

The NOX1 protein contains two isoforms with different functions. NOH-1S acts as a voltage-gated proton channel, manages H(+) currents in quiescent phagocytes and tissues, affects cellular pH, and is inhibited by zinc. NOX1 Protein, Human (Cell-Free, His) is the recombinant human-derived NOX1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of NOX1 Protein, Human (Cell-Free, His) is 564 a.a., with molecular weight of 67.7 kDa.

NOX1 蛋白包含两种具有不同功能的不同亚型。NOH-1S 作为电压门控质子通道运行，主要在静态吞噬细胞和各种组织中协调 H(+) 电流。该异构体积极参与细胞 pH 值的调节，并且容易受到锌的抑制。另一方面，NOH-1L 作为吡啶核苷酸依赖性氧化还原酶发挥作用，表现出产生超氧化物的能力，同时作为其电子传递机制的一部分，可能促进 H(+) 离子的传导。值得注意的是，NOH-1S 缺乏电子传输链，这使其功能特性与 NOH-1L 不同。

Human

E. coli Cell-free

N-10*His

Q9Y5S8 (M1-F564)

27035

MGNWVVNHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTLILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCYSRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALILMVTSATEFIRRSYFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAESFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVVITKVVMHPSKVLELQMNKRGFSMEVGQYIFVNCPSISLLEWHPFTLTSAPEEDFFSIHIRAAGDWTENLIRAFEQQYSPIPRIEVDGPFGTASEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADHNLKTKKIYFYWICRETGAFSWFNNLLTSLEQEMEELGKVGFLNYRLFLTGWDSNIVGHAALNFDKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCCHRYSSLDPRKVQFYFNKENF

67.7 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.