2. 重组蛋白
  3. Receptor Proteins
  4. G-Protein-Coupled Receptors (GPCRs)
  5. OX2R 蛋白, Human (Sf9, FLAG, His)

OX2R 蛋白, Human (Sf9, FLAG, His)

目录号: HY-P702084
COA 产品使用指南

OX2R 蛋白是一种非选择性、高亲和力受体，是食欲素 A 和食欲素 B 神经肽的关键结合位点。它与食欲素-A 的相互作用导致细胞质 Ca(2+) 水平显着增加，表明它参与与神经肽激活相关的细胞反应。OX2R 蛋白, Human (Sf9, FLAG, His) 是重组的蛋白二聚体复合物，包含 OX2R 蛋白，由 Sf9 insect cells 表达，带有 N-Flag, C-10*His 标签。OX2R 蛋白, Human (Sf9, FLAG, His) ，分子量为 64.6 kDa。

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描述

OX2R Protein, a nonselective, high-affinity receptor, functions as a key binding site for orexin-A and orexin-B neuropeptides. Its interaction with orexin-A leads to a significant increase in cytoplasmic Ca(2+) levels, indicating its involvement in cellular responses associated with neuropeptide activation. OX2R Protein, Human (Sf9, FLAG, His) is a recombinant protein dimer complex containing human-derived OX2R protein, expressed by Sf9 insect cells , with N-Flag, C-10*His labeled tag. OX2R Protein, Human (Sf9, FLAG, His), has molecular weight of 64.6 kDa.
研究背景

OX2R 蛋白是一种非选择性、高亲和力受体，是食欲素 A 和食欲素 B 神经肽的关键结合位点。与食欲素-A 结合后，OX2R 会引发细胞质 Ca(2+) 水平显着升高，这表明其在协调与这些神经肽激活相关的细胞反应中的作用。
种属

Human
表达系统

Sf9 insect cells
标签

N-Flag;C-10*His
蛋白编号

O43614 (M1-Q254&K294-H388)
基因 ID

3062
同用名
HCRTR2; Orexin receptor type 2; Ox-2-R; Ox2-R; Ox2R; Hypocretin receptor type 2
分子量

64.6 KDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

/
文件资料

COA (210 KB)

产品使用指南 (1213 KB)

OX2R Protein, Human (Sf9, FLAG, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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