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  3. PVALB 蛋白, Human (His)

PVALB 蛋白, Human (His)

目录号: HY-P71129
产品使用指南

PVALB 蛋白,也称为小白蛋白,通过促进收缩后的松弛而在肌肉组织中发挥关键作用。其功能涉及结合两个钙离子,这表明在调节肌肉细胞内的钙动态方面发挥着至关重要的作用。小白蛋白螯合钙的能力强调了其在微调收缩和松弛之间的平衡方面的重要性,有助于整体肌肉生理控制。PVALB 蛋白, Human (His) 是重组的 PVALB 蛋白,由 E. coli 表达,带有 C-6*His 标签。PVALB 蛋白, Human (His) 全长 109 个氨基酸,分子量约为 ~14.0 kDa。

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描述

PVALB Protein, also known as parvalbumin, plays a key role in muscle tissue by facilitating relaxation after contraction. Its function involves binding two calcium ions, indicating a crucial role in regulating calcium dynamics within muscle cells. Parvalbumin's ability to sequester calcium underscores its significance in fine-tuning the balance between contraction and relaxation, contributing to overall muscle physiology control. PVALB Protein, Human (His) is the recombinant human-derived PVALB protein, expressed by E. coli , with C-6*His labeled tag. The total length of PVALB Protein, Human (His) is 109 a.a., with molecular weight of ~14.0 kDa.

研究背景

在肌肉组织中,PVALB 蛋白(通常称为小清蛋白)参与收缩后的松弛过程。其功能作用集中于结合两个钙离子,这表明在调节肌肉细胞内的钙动态方面发挥着至关重要的作用。这种螯合钙的能力强调了小清蛋白在微调收缩和松弛之间复杂的平衡方面的重要性,有助于肌肉生理学的整体控制。

种属

Human

表达系统

E. coli

标签

C-6*His

蛋白编号

P20472 (S2-S110)

基因 ID
蛋白结构
N-term
PVALB (S2-S110)
Accession # P20472
6*His
C-term
同用名
Parvalbumin Alpha; PVALB
氨基酸序列

SMTDLLNAEDIKKAVGAFSATDSFDHKKFFQMVGLKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES

分子量

Approximately 14.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PVALB Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PVALB Protein, Human (His)
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