SLC14A1 蛋白, Human (Cell-Free, His)

SLC14A1 Protein plays a pivotal role in cellular processes, mediating urea transport across erythrocyte and renal inner medullary collecting duct membranes. It is crucial for the urinary concentrating mechanism and regulates water transport in erythrocytes. With a dual role in urea transport, SLC14A1 maintains cellular osmotic balance and contributes to physiological processes associated with urinary concentration, highlighting its significance. SLC14A1 Protein, Human (Cell-Free, His) is the recombinant human-derived SLC14A1 protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of SLC14A1 Protein, Human (Cell-Free, His) is 389 a.a., with molecular weight of 48.6 kDa.

SLC14A1 蛋白在浓度梯度的驱动下介导尿素穿过红细胞细胞膜的转运，从而在细胞过程中发挥关键作用。此外，SLC14A1 通过介导尿素穿过肾内髓质集合管细胞膜的转运，在尿液浓缩机制中发挥着至关重要的作用。该功能对于红细胞中水运输的调节是不可或缺的。该蛋白质在尿素转运中的双重作用强调了其在维持细胞渗透平衡和促进与尿液浓度相关的生理过程中的重要性。

Human

E. coli Cell-free

N-10*His

Q13336 (M1-L389)

6563

MEDSPTMVRVDSPTMVRGENQVSPCQGRRCFPKALGYVTGDMKELANQLKDKPVVLQFIDWILRGISQVVFVNNPVSGILILVGLLVQNPWWALTGWLGTVVSTLMALLLSQDRSLIASGLYGYNATLVGVLMAVFSDKGDYFWWLLLPVCAMSMTCPIFSSALNSMLSKWDLPVFTLPFNMALSMYLSATGHYNPFFPAKLVIPITTAPNISWSDLSALELLKSIPVGVGQIYGCDNPWTGGIFLGAILLSSPLMCLHAAIGSLLGIAAGLSLSAPFEDIYFGLWGFNSSLACIAMGGMFMALTWQTHLLALGCALFTAYLGVGMANFMAEVGLPACTWPFCLATLLFLIMTTKNSNIYKMPLSKVTYPEENRIFYLQAKKRMVESPL

48.6 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.