SLC5A2 蛋白, Human (Cell-Free, His, SUMO, Myc)

The SLC5A2 protein, as an electrogenic Na(+)-coupled sugar symporter, actively promotes D-glucose transport across the plasma membrane with a precise Na(+) to sugar coupling ratio of 1:1. As observed in various studies, transporter activity is powered by the transmembrane Na(+) electrochemical gradient established by the Na(+)/K(+) pump. SLC5A2 Protein, Human (Cell-Free, His, SUMO, Myc) is the recombinant human-derived SLC5A2 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc, N-SUMO labeled tag. The total length of SLC5A2 Protein, Human (Cell-Free, His, SUMO, Myc) is 102 a.a., with molecular weight of 30.5 kDa.

SLC5A2 是一种产电 Na(+) 偶联糖同向转运蛋白，负责主动转运 D-葡萄糖穿过质膜，Na(+) 与糖的偶联比为 1:1。转运蛋白的活性依赖于由Na(+)/K(+)泵建立的跨膜Na(+)电化学梯度。首先，SLC5A2 在肾小球滤液中 D-葡萄糖的重吸收中发挥着至关重要的作用，在肾脏早期近端小管的刷状缘发挥作用。这种协同转运蛋白的活性对于通过有效地从滤液中回收葡萄糖来维持葡萄糖稳态至关重要，有助于体内葡萄糖的整体肾脏处理。

Human

E. coli Cell-free

N-10*His;C-Myc;N-SUMO

P31639 (M1-A102)

6524

MEEHTEAGSAPEMGAQKALIDNPADILVIAAYFLLVIGVGLWSMCRTNRGTVGGYFLAGRSMVWWPVGASLFASNIGSGHFVGLAGTGAASGLAVAGFEWNA

30.5 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.