1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. TMPRSS11E 蛋白, Human (HEK293, His)

TMPRSS11E 蛋白, Human (HEK293, His)

目录号: HY-P701044
产品使用指南

TMPRSS11E 是一种丝氨酸蛋白酶,具有双重酶活性,包括明胶分解和酪蛋白分解,并且优先考虑 P1 位的精氨酸。其蛋白水解功能被 SERPINA5 抑制,强调了控制酶活性的调节机制。TMPRSS11E 蛋白, Human (HEK293, His) 是重组的 TMPRSS11E 蛋白,由 HEK293 表达,带有 C-His 标签。TMPRSS11E 蛋白, Human (HEK293, His) 全长 383 个氨基酸,分子量为 30-35 kDa。

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描述

TMPRSS11E, a serine protease, shows dual enzymatic activities, including gelatinolysis and caseinolysis, with a preference for Arginine in the P1 position. Its proteolytic function is inhibited by SERPINA5, underscoring regulatory mechanisms in controlling enzymatic activity. TMPRSS11E Protein, Human (HEK293, His) is the recombinant human-derived TMPRSS11E protein, expressed by HEK293 , with C-His labeled tag. The total length of TMPRSS11E Protein, Human (HEK293, His) is 383 a.a., with molecular weight of 30-35 kDa.

研究背景

TMPRSS11E 是一种丝氨酸蛋白酶,具有双重酶活性,具有分解明胶和分解酪蛋白的功能。值得注意的是,它在 P1 位显示出对精氨酸的偏好,突出了其底物特异性。此外,TMPRSS11E 的蛋白水解活性受到 SERPINA5 的抑制,这强调了控制其酶功能的调节机制。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

Q9UL52 (H41-I423)

基因 ID
蛋白结构
N-term
TMPRSS11E (H41-I423)
Accession # Q9UL52
His
C-term
同用名
Serine protease DESC1; TMPRSS11E; DESC1; TMPRSS11E2
分子量

30-35 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TMPRSS11E Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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TMPRSS11E Protein, Human (HEK293, His)
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HY-P701044
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