2. Others Neuronal Signaling GPCR/G Protein
  3. Dopamine Receptor Isotope-Labeled Compounds
  4. Ropinirole-d4 hydrochloride

Ropinirole-d4 hydrochloride  (Synonyms: SKF 101468-d4 hydrochloride)

目录号: HY-B0623AS
产品使用指南 技术支持

Ropinirole-d4 (SKF 101468-d4) hydrochloride 是 Ropinirole hydrochloride 的氘代物。Ropinirole hydrochloride 是一种有效的 D3/D2 受体激动剂，对 D2 受体的 Ki 为 29 nM。Ropinirole hydrochloride 对 hD2，hD3 和 hD4 受体的 pEC50 分别为 7.4、8.4 和 6.8。Ropinirole hydrochloride 对 D1 受体没有亲和力。Ropinirole hydrochloride 具有用于帕金森氏病潜力。

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Ropinirole-d<sub>4</sub> hydrochloride Chemical Structure

Ropinirole-d4 hydrochloride Chemical Structure

CAS No. : 1330261-37-4

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Other Forms of Ropinirole-d4 hydrochloride:

Ropinirole-d4 hydrochloride 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Ropinirole-d4 (SKF 101468-d4) hydrochloride is the deuterium labeled Ropinirole hydrochloride. Ropinirole hydrochloride is a potent D3/D2 receptor agonist with a Kiof 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson's disease[1][2].

IC50 & Target

D3 Receptor

 

D4 Receptor

 

D2 Receptor

 

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ropinirole-d4 hydrochloride 相关抗体:
分子量

300.86

同用名

SKF 101468-d4 hydrochloride

Formula

C16H21D4ClN2O
CAS 号
非标记 CAS
中文名称

盐酸罗匹尼罗 d4 (盐酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ropinirole-d4 hydrochloride 相关分类

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Keywords:

Ropinirole-d41330261-37-4SKF 101468-d4盐酸罗匹尼罗 d4 (盐酸盐)Dopamine ReceptorIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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