2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. iGluR
  4. Sepimostat dimethanesulfonate

Sepimostat dimethanesulfonate  (Synonyms: FUT-187)

目录号: HY-136299A
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摩尔计算器

Sepimostat dimethanesulfonate (FUT-187) 通过拮抗 NR2B N-methyl-D-aspartate 受体发挥神经保护作用， 作用位点在NR2B 亚基的 Ifenprodil 结合位点。Sepimostat dimethanesulfonate 抑制 Ifenprodil 结合的 Ki 值为 27.7 µM。

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Sepimostat dimethanesulfonate Chemical Structure

Sepimostat dimethanesulfonate Chemical Structure

CAS No. : 103926-82-5

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Sepimostat dimethanesulfonate 的其他形式现货产品:

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Sepimostat dimethanesulfonate 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7 µM[1].

体内研究
(In Vivo)

Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague Dawley rats weighing 150-300 g[1].
Dosage: Intravitreal injection.
Administration: 1 to 100 nmol/eye.
Result: Exhibited neuroprotective effects significantly.
分子量

565.62

Formula

C23H27N5O8S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sepimostat dimethanesulfonate 相关分类

  • 摩尔计算器

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Keywords:

Sepimostat103926-82-5FUT-187FUT187FUT 187iGluRIonotropic glutamate receptorsInhibitorinhibitorinhibit

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