2. PROTAC
  3. E3 Ligase Ligand-Linker Conjugates
  4. Thalidomide-PEG2-C2-NH2 hydrochloride

Thalidomide-PEG2-C2-NH2 hydrochloride  (Synonyms: Thalidomide-NH-PEG2-C2-NH2 hydrochloride)

目录号: HY-129703B
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摩尔计算器

Thalidomide-PEG2-C2-NH2 hydrochloride 是一种合成的 E3 连接酶配体-linker 偶联物，包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker。

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Thalidomide-PEG2-C2-NH2 hydrochloride Chemical Structure

Thalidomide-PEG2-C2-NH2 hydrochloride Chemical Structure

CAS No. : 2245697-87-2

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规格 价格 是否有货 数量
5 mg ￥500
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10 mg ￥700
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25 mg ￥1400
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50 mg ￥2200
In-stock
100 mg ￥3500
In-stock
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500 mg   询价  

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Other Forms of Thalidomide-PEG2-C2-NH2 hydrochloride:

Thalidomide-PEG2-C2-NH2 hydrochloride 相关抗体

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查看 E3 Ligase Ligand-Linker Conjugates 亚型特异性产品:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Thalidomide-PEG2-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Thalidomide-PEG2-C2-NH2 hydrochloride 相关抗体:
分子量

440.88

Formula

C19H25ClN4O6
CAS 号
性状

固体

颜色

Light yellow to green yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Thalidomide-PEG2-C2-NH2 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thalidomide-PEG2-C2-NH22245697-87-2Thalidomide-NH-PEG2-C2-NH2E3 Ligase Ligand-Linker ConjugatesE3ligaseligand-linkerconjugatePEG3PROTACInhibitorinhibitorinhibit

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目录号：
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