2. Metabolic Enzyme/Protease
  3. HIF/HIF Prolyl-Hydroxylase
  4. Zifcasiran

Zifcasiran  (Synonyms: ADS-007; ARO HIF2)

目录号: HY-147426
产品使用指南

摩尔计算器

Zifcasiran 是一种缺氧诱导因子 (HIF) 合成抑制剂，并表现出抗肿瘤活性，可用于晚期肾细胞癌的研究。

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RNA, (Cm-sp-Am-Am-Cm-Gm-Um-Am-Am-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)G-(2′-deoxy-2′-fluoro)A-Um-Um-[2′-O-[[1-[2-[2-[2-[2-[2-fluoro-4-[(1S)-3-hydroxy-3-oxo-1-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]propyl]phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methyl]]U-Cm-[2′-O-[[1-[2-[2-[2-[2-[2-fluoro-4-[(1S)-3-hydroxy-3-oxo-1-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]propyl]phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methyl]]A-Um-[2′-O-[[1-[2-[2-[2-[2-[2-fluoro-4-[(1S)-3-hydroxy-3-oxo-1-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]propyl]phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methyl]]G-Am-[2′-O-[[1-[2-[2-[2-[2-[2-fluoro-4-[(1S)-3-hydroxy-3-oxo-1-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]propyl]phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methyl]]A-Am-(3′→3′)-sp-[1′-de(6-amino-9H-purin-

Zifcasiran Chemical Structure

CAS No. : 2437257-11-7

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规格 是否有货
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Zifcasiran 相关抗体

Top Publications Citing Use of Products

查看 HIF/HIF Prolyl-Hydroxylase 亚型特异性产品:

查看所有亚型
HIF-1α HIF

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Zifcasiran is a hypoxia-inducible factor (HIF) synthesis reducer. Zifcasiran shows antitumor activities and can be used in advanced renal cell carcinoma research[1][2].

分子量

20339.13

Formula

C737H972F20N211O349P43S8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Zifcasiran 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zifcasiran2437257-11-7ADS-007 ARO HIF2ADS007ADS 007ARO HIF2ARO HIF 2ARO HIF-2HIF/HIF Prolyl-HydroxylaseHypoxia-inducible factorsHIFsHIF-PHantitumor activityadvanced renal cell carcinomaInhibitorinhibitorinhibit

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