2. Protein Tyrosine Kinase/RTK
  3. VEGFR
  4. Ziv-aflibercept

Ziv-aflibercept 

目录号: HY-108798 纯度: 95.00%
COA

摩尔计算器

Ziv-aflibercept 是一种可溶性的血管内皮生长因子 (VEGF) 抑制剂。Ziv-aflibercept 是 Aflibercept (HY-108801) 的自适应变体，与 Aflibercept 相比，Ziv-aflibercept 具有低 PH 值和高渗透压。Ziv-aflibercept 在转移性结直肠癌和视网膜疾病中有潜在应用。

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Ziv-aflibercept Chemical Structure

Ziv-aflibercept Chemical Structure

CAS No. : 1609655-49-3

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规格 价格 是否有货 数量
1 mg ￥6000
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Ziv-aflibercept 相关抗体

Top Publications Citing Use of Products

查看 VEGFR 亚型特异性产品:

查看所有亚型
VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ziv-aflibercept is a soluble inhibitor of vascular endothelial growth factor (VEGF). Ziv-aflibercept is an adaptive variant of Aflibercept (HY-108801), Ziv-aflibercept has a low PH value and high osmotic pressure when compared to Aflibercept. Ziv-aflibercept has potential applications in metastatic colorectal carcinoma and retinal diseases[1][2].

体外研究
(In Vitro)

Ziv-aflibercept (0.25、0.5、1.0 和 5 mg/mL；24 h) 以剂量依赖性方式降低 ARPE-19 细胞的线粒体膜电位[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Ziv-aflibercept 相关抗体:

Cell Viability Assay[1]

Cell Line: ARPE-19 cells.
Concentration: 0.25, 0.5, 1.0 and 5 mg/mL.
Incubation Time: 24 h.
Result: Insignificantly affected cell viability (below 1 mg/mL).
体内研究
(In Vivo)

Ziv-aflibercept (25 mg/mL；眼内注射；单剂量) 在兔子右眼中没有显著引起白内障、视网膜脱离等相关并发症[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Ziv-aflibercept 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ziv-aflibercept1609655-49-3VEGFRVascular endothelial growth factor receptorARPE-19 cellsRabbitInhibitorinhibitorinhibit

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目录号：
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