1. Metabolic Enzyme/Protease GPCR/G Protein
  2. Prostaglandin Receptor Cytochrome P450
  3. 5-trans-PGE2

5-trans-PGE2  (Synonyms: 5-trans Prostaglandin E2)

目录号: HY-135023
产品使用指南

5-trans-PGE2 (5-trans Prostaglandin E2) 是 PGE2 的活性异构体,是芳香酶的有效激活剂。补充了上皮细胞(表达高水平 PGE2)和周围基质细胞(表达高水平芳香化酶)之间的旁分泌信号的传递过程。该过程与乳腺癌的生长和发展有关。

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5-trans-PGE2 Chemical Structure

5-trans-PGE2 Chemical Structure

CAS No. : 36150-00-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-trans-PGE2 (5-trans Prostaglandin E2) is the active isomer of PGE2 and a potent activator of aromatase. Supplements the process of paracrine signaling between epithelial cells (expressing high levels of PGE2) and surrounding stromal cells (expressing high levels of aromatase). This process is involved in the growth and development of breast cancer[1].

分子量

352.47

Formula

C20H32O5

CAS 号
中文名称

5反式前列腺素E2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-135023
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