1. Others
  2. Others
  3. ATWLPPR Peptide TFA

ATWLPPR Peptide TFA 

目录号: HY-P1663A 纯度: 98.99%
产品使用指南

ATWLPPR Peptide TFA 是一种选择性的 neuropilin-1 (NRP-1) 抑制剂,能够抑制 VEGF165 与 NRP-1 结合,可用于血管生成的研究。ATWLPPR Peptide TFA 能够减轻糖尿病引起的早期视网膜损伤。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

ATWLPPR Peptide TFA Chemical Structure

ATWLPPR Peptide TFA Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Price Stock Quantity
10 mM * 1 mL in Water ¥26235 In-stock
1 mg ¥2500 In-stock
5 mg   Get quote  
10 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

ATWLPPR Peptide TFA, a heptapeptide, acts as a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1, used in the research of angiogenesis[1]. ATWLPPR Peptide TFA has potential in reducing the early retinal damage caused by diabetes[2].

IC50 & Target

Neuropilin-1[2]

In Vitro

ATWLPPR Peptide TFA is a selective neuropilin-1 inhibitor, inhibits VEGF165 binding to NRP-1 by 82% at 100 μM[1].

In Vivo

ATWLPPR (400 μg/kg, s.c.) preserves vascular integrity and decreases the oxidative stress level, possibly reduces the early retinal damage caused by diabetes[2].
ATWLPPR prevents the increase of inflammation-associated proteins (GFAP, VEGF and ICAM-1) in the retina[2].

Molecular Weight

954.00

Formula

C₄₂H₆₂F₃N₁₁O₁₁

SMILES

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC(C)C)C(N3[C@@H](CCC3)C(N4[C@@H](CCC4)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)[C@H](C)N.OC(C(F)(F)F)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Protect from light
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (52.41 mM)

* "≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0482 mL 5.2411 mL 10.4822 mL
5 mM 0.2096 mL 1.0482 mL 2.0964 mL
10 mM 0.1048 mL 0.5241 mL 1.0482 mL
* 请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液,并请注意储备液的保存方式和期限。
References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
ATWLPPR Peptide TFA
目录号:
HY-P1663A
需求量:

ATWLPPR Peptide TFA

Cat. No.: HY-P1663A