2. Others GPCR/G Protein Neuronal Signaling
  3. Isotope-Labeled Compounds Dopamine Receptor
  4. Rotigotine-d7 hydrochloride

Rotigotine-d7 hydrochloride  (Synonyms: 罗替戈汀 D7 盐酸盐; N-0923 D7 Hydrochloride)

目录号: HY-A0007S
产品使用指南 技术支持

Rotigotine-d7 (N-0923-d7) hydrochloride 是氘代标记的 Rotigotine(HY-75502)。Rotigotine 是一种有效的多巴胺受体激动剂 (dopamine receptor)，其 Ki 值为 0.71 nM (dopamine D3 receptor)，4-15 nM (D2，D5，D4 receptors)，83 nM (dopamine D1 receptor)。Rotigotine 是 5-HT1A receptor 的部分激动剂和 α2B-adrenergic receptor 的拮抗剂。Rotigotine 可用于帕金森病（PD）研究。

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Rotigotine-d<sub>7</sub> hydrochloride

Rotigotine-d7 hydrochloride Chemical Structure

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Other Forms of Rotigotine-d7 hydrochloride:

Rotigotine-d7 hydrochloride 相关抗体

Top Publications Citing Use of Products

查看 Dopamine Receptor 亚型特异性产品:

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 纯度 & 产品资料

生物活性

Rotigotine-d7 (N-0923-d7) hydrochloride is the deuterium labeled Rotigotine(HY-75502). Rotigotine is a potent dopamine receptor agonist with Ki values of 0.71 nM, 4-15 nM, and 83 nM for the dopamine D3 receptor and D2, D5, D4 receptors and dopamine D1 receptor. Rotigotine a partial agonist of the 5-HT1A receptor, and an antagonist of the α2B-adrenergic receptor. Rotigotine can be used for parkinson's disease (PD) research.

产品应用

1. 该化合物可作为示踪剂。
2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。
体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Rotigotine-d7 hydrochloride 相关抗体:
分子量

358.98

Formula

C19H19D7ClNOS
非标记 CAS
中文名称

罗替戈汀盐酸盐 d7
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Rotigotine-d7 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rotigotine-d7N-0923 D7罗替戈汀盐酸盐 d7Isotope-Labeled CompoundsDopamine ReceptorInhibitorinhibitorinhibit

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