2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. HSP
  4. A8 peptide

A8 peptide 是一种 Hsp72 拮抗剂。A8 peptide 通过阻断 Hsp72-TLR2 相互作用以及随后的 MDSCs 激活，进而抑制肿瘤进展和转移，并增强癌细胞对化疗药物 (如 Cisplatin (HY-17394)) 诱导的细胞凋亡敏感性。A8 peptide 可用于癌症研究。

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Custom Peptide Synthesis

A8 peptide

A8 peptide Chemical Structure

CAS No. : 1140483-17-5

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A8 peptide 相关抗体

Top Publications Citing Use of Products

查看 HSP 亚型特异性产品:

查看所有亚型
HSP40 HSP70 HSP90 HSP105 HSF1 HSP HSPA5

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

A8 peptide is a Hsp72 antagonist. A8 peptide inhibits tumor progression and metastasis as well as enhances the cancer cells' sensitivity to apoptosis induced by chemotherapeutic agents (such as Cisplatin (HY-17394)) by blocking the Hsp72-TLR2 interaction and the subsequent activation of MDSCs. A8 peptide can be used for cancers research[1].

IC50 & Target[1]

HSP72

 

分子量

1003.11

Formula

C48H66N12O12
CAS 号
Sequence

Ser-Pro-Trp-Pro-Arg-Pro-Thr-Tyr
Sequence Shortening

SPWPRPTY
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

A8 peptide 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

A8 peptide1140483-17-5HSPHeat shock proteinsAntagonistHsp72Hsp72-TLR2 interactionApoptosisCisplatinMDSCsCancersInhibitorinhibitorinhibit

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目录号：
HY-P11052
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