2. PI3K/Akt/mTOR NF-κB MAPK/ERK Pathway Apoptosis Immunology/Inflammation
  3. Akt NF-κB JNK TNF Receptor COX
  4. Akt/NF-κB/JNK-IN-1

Akt/NF-κB/JNK-IN-1 (Compound 2i) 是一种 Akt, NF-κB 和 JNK 信号通路抑制剂。Akt/NF-κB/JNK-IN-1 抑制一氧化氮的产生，IC50 为 3.15 μM。Akt/NF-κB/JNK-IN-1 具有抗炎活性。

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Akt/NF-κB/JNK-IN-1 Chemical Structure

Akt/NF-κB/JNK-IN-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Akt/NF-κB/JNK-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Akt 亚型特异性产品:

查看所有亚型
Akt Akt1 Akt2 Akt3

查看 NF-κB 亚型特异性产品:

查看所有亚型
NF-κB NF-κB1/p50 RelA/p65 RelB c-Rel

查看 JNK 亚型特异性产品:

查看所有亚型
JNK1 JNK2 JNK3 JNK

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Akt/NF-κB/JNK-IN-1 (Compound 2i) is an inhibitor of Akt, NF-κB and JNK signaling pathways. Akt/NF-κB/JNK-IN-1 inhibits nitric oxide production with an IC50 of 3.15 μM. Akt/NF-κB/JNK-IN-1 shows anti-inflammatory activities[1].

IC50 & Target

COX-2

 

体外研究
(In Vitro)

Akt/NF-κB/JNK-IN-1 (Compound 2i) (0-50 μM) significantly reduces the levels of TNF-α, IL-1β, IL-6 and PGE2 and markedly downregulates the expression levels of iNOS and COX-2[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Akt/NF-κB/JNK-IN-1 相关抗体:
分子量

410.42

Formula

C22H22N2O6
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Akt/NF-κB/JNK-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Akt/NF-κB/JNK-IN-1AktNF-κBJNKTNF ReceptorCOXPKBProtein kinase BNuclear factor-κBNuclear factor-kappaBc-Jun N-terminal kinaseTumor Necrosis Factor ReceptorTNFRCyclooxygenaseanti-inflammatoryRAW264.7TNF-αIL-1βIL-6PGE2Inhibitorinhibitorinhibit

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产品名称：
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