1. Protein Tyrosine Kinase/RTK PI3K/Akt/mTOR
  2. Insulin Receptor Akt
  3. Anti-CD220/Insulin Receptor Antibody (IR 83-22)

Anti-CD220/Insulin Receptor Antibody (IR 83-22) 

目录号: HY-P990867
技术支持

Anti-CD220/Insulin Receptor Antibody (IR 83-22) 是一种抗人的 CD220/Insulin Receptor IgG1 单克隆抗体。Anti-CD220/Insulin Receptor Antibody (IR 83-22) 可以阻断 Trip13 缺乏引起的 Akt 过度激活。Anti-CD220/Insulin Receptor Antibody (IR 83-22) 可用于癌症如肝细胞癌 (HCC) 的研究。Anti-CD220/Insulin Receptor Antibody (IR 83-22) 常用于蛋白质印迹。Anti-CD220/Insulin Receptor Antibody (IR 83-22) 的同型对照为 Mouse IgG1 kappa, Isotype Control (HY-P99977)。

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Anti-CD220/Insulin Receptor Antibody (IR 83-22)

Anti-CD220/Insulin Receptor Antibody (IR 83-22) Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-CD220/Insulin Receptor Antibody (IR 83-22) is an anti-human CD220/Insulin Receptor IgG1 monoclonal antibody. Anti-CD220/Insulin Receptor Antibody (IR 83-22) can block Akt overactivation caused by Trip13 deficiency. Anti-CD220/Insulin Receptor Antibody (IR 83-22) can be used for research on cancer such as hepatocellular carcinoma (HCC). Anti-CD220/Insulin Receptor Antibody (IR 83-22) often used in western blotting. The recommend isotype control of Anti-CD220/Insulin Receptor Antibody (IR 83-22): Mouse IgG1 kappa, Isotype Control (HY-P99977)[1][2].

同型

Mouse IgG1 kappa

反应种属

Human

IC50 & Target

CD220/Insulin Receptor

体外研究
(In Vitro)

Anti-CD220/Insulin Receptor Antibody (IR 83-22) (10 μg/mL,30 分钟) 可以逆转 HLF 细胞中 Trip13 敲除诱导的 Akt 磷酸化上调[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

基因 ID

3643  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-CD220/Insulin Receptor Antibody (IR 83-22)
目录号:
HY-P990867
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