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  3. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1)

Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 

目录号: HY-P990304B
技术支持

Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 是一种源自小鼠的 IgG1 κ 抗体抑制剂,靶向小鼠 4-1BBL/CD137L。Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 是原始 TKS-1 抗体 (HY-P990304) 的嵌合版本。其可变区序列与原始 TKS-1 相同,但恒定区序列已从大鼠 IgG2a 转换为小鼠 IgG1。Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 在 Fc 片段中含有 D265A 突变,使其无法结合内源性 Fcγ 受体。Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 与小鼠 4-1BB 配体 (4-1BBL) 发生反应。Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) 可用于癌症、感染、炎症和免疫学研究。

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Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1)

Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) is a mouse-derived IgG1 κ antibody inhibitor that targets mouse 4-1BBL/CD137L. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) is a chimeric version of the original TKS-1 antibody (HY-P990304). The variable domain sequences are identical to the original TKS-1 but the constant region sequences have been switched from rat IgG2a to mouse IgG1. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) contains a D265A mutation in the Fc fragment rendering it unable to bind to endogenous Fcγ receptors. Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) reacts with mouse 4-1BB ligand (4-1BBL). Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1) can be used for the researches of cancer, infection, inflammation and immunology.

同型

Mouse IgG1 (D265A) kappa

推荐同型对照抗体
反应种属

Mouse

IC50 & Target

4-1BBL/CD137L (D265A)

基因 ID

21950  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Mouse 4-1BBL/CD137L (D265A) Antibody (TKS-1)
目录号:
HY-P990304B
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