1. Immunology/Inflammation
  2. Transmembrane Glycoprotein
  3. Anti-Mouse CD24 Antibody (M1/69)

Anti-Mouse CD24 Antibody (M1/69) 

目录号: HY-P990282 纯度: ≥95.0%
COA 技术支持

Anti-Mouse CD24 Antibody (M1/69) 是一种源自大鼠的抗小鼠 CD24 IgG2b κ 型抗体抑制剂。Anti-Mouse CD24 Antibody (M1/69) 可以降低野生型 HSA+/+ 小鼠中热稳定抗原 (HSA) 的表达水平并延缓伤口愈合。

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Anti-Mouse CD24 Antibody (M1/69)

Anti-Mouse CD24 Antibody (M1/69) Chemical Structure

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规格 价格 是否有货 数量
1 mg ¥2200
In-stock
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anti-Mouse CD24 Antibody (M1/69) is a rat-derived anti-mouse CD24 IgG2b κ type antibody inhibitor. Anti-Mouse CD24 Antibody reduces heat stable antigen (HSA) expression level and delays wound healing in Wild-type HSA+/+ mice[1][2].

同型

Rat IgG2b kappa

推荐同型对照抗体
反应种属

Mouse

IC50 & Target

CD24

体外研究
(In Vitro)

抗体框架具有稳定性、特异性和适应性,同时具有结合抗原和内源免疫受体。 单克隆抗体具有几种衍生物,包括双特异性抗体、抗体-药物缀合物和抗体片段,在免疫学和肿瘤学等领域具有显著效果。 设计抑制性抗体时,需要注意包括抗原特异性可变区的鉴定、表达系统的选择、多特异性形式的使用以及基于片段化、寡聚化或与其他功能部分缀合的抗体衍生物[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Anti-Mouse CD24 Antibody (M1/69) (10 mg/kg,通过局部注射到伤口边缘的细胞中) 降低野生型 HSA+/+ 小鼠的热稳定抗原 (HAS) 表达水平,并导致愈合速度减慢且不均匀[1]
Anti-Mouse CD24 Antibody (M1/69) (5 mg/kg,静脉注射,单剂量) 可在负荷 KHOS 肿瘤的模型小鼠中精准识别并靶向原位骨肉瘤肿瘤[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wild-type HAS(heat stable antigen)+/+ mice[1]
Dosage: 10 mg/kg
Administration: Administrated topically by injection into the cells on the wound border
Result: Reduced HSA expression level and caused slower and non-homogenous healing.
基因 ID

12484  [NCBI]

Accession
应用

ELISA, FACS, Functional assay, Research in vivo

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

分子量

150 kDa

性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料

纯度: ≥95.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Anti-Mouse CD24 Antibody (M1/69)
目录号:
HY-P990282
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