1. PROTAC
    Antibody-drug Conjugate/ADC Related
  2. PROTAC Linker
    ADC Linker
  3. Azido-PEG2-C2-amine

Azido-PEG2-C2-amine (Synonyms: N3-PEG2-CH2CH2NH2)

目录号: HY-140213
产品使用指南

Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) 是一种 PROTAC linker,属于 PEG 类,可用于合成 PROTAC 分子。Azido-PEG2-C2-amine 也是一种不可降解 (non-cleavable) 的含 2 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

Azido-PEG2-C2-amine Chemical Structure

Azido-PEG2-C2-amine Chemical Structure

CAS No. : 166388-57-4

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products

View All PROTAC Linker Isoform Specific Products:

View All ADC Linker Isoform Specific Products:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

Azido-PEG2-C2-amine (N3-PEG2-CH2CH2NH2) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-C2-amine is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

IC50 & Target[1][2]

PEGs

 

Non-cleavable

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

Molecular Weight

174.20

Formula

C₆H₁₄N₄O₂

CAS No.

166388-57-4

SMILES

[N-]=[N+]=NCCOCCOCCN

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Azido-PEG2-C2-amineN3-PEG2-CH2CH2NH2PROTAC LinkerADC LinkerAntibody-drug conjugates linkerPEGADClinkerPROTACnon-cleavableInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Azido-PEG2-C2-amine
目录号:
HY-140213
需求量: