2. Others Epigenetics Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. PARP Isotope-Labeled Compounds Endogenous Metabolite
  4. Benzamide-d5

Benzamide-d5  (Synonyms: Benzenecarboxamide-d5; Phenylamide-d5)

目录号: HY-W711852
产品使用指南 技术支持

Benzamide-d5 (Benzenecarboxamide-d5) 是氘代标记的 Benzamide. Benzamide (Benzenecarboxamide) 是一种有效的 PARP 抑制剂。Benzamide 对谷氨酸和 methamphetamine (METH) 诱导的神经毒性均有体外保护作用。Benzamide 能减轻 METH 诱导的小鼠多巴胺消耗，并表现出神经保护活性，对纹状体多巴胺代谢没有急性影响，也不降低体温。

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Benzamide-d<sub>5</sub>

Benzamide-d5 Chemical Structure

CAS No. : 1235489-47-0

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规格 价格 是否有货 数量
5 mg ￥1800
3 - 4 周
10 mg ￥2700
3 - 4 周
25 mg ￥4050
3 - 4 周
50 mg ￥5260
3 - 4 周
100 mg 询价 3 - 4 周
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Other Forms of Benzamide-d5:

Benzamide-d5 相关抗体

Top Publications Citing Use of Products

查看 PARP 亚型特异性产品:

查看所有亚型
PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Benzamide-d5 (Benzenecarboxamide-d5) is deuterium labeled Benzamide. Benzamide (Benzenecarboxamide) is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Benzamide has protective activity against both glutamate- and methamphetamine (METH)-induced neurotoxicity in vitro. Benzamide can attenuate the METH-induced dopamine depletions and exhibits neuroprotective activity in mice, also has no acute effect on striatal dopamine metabolism and does not reduce body temperature[1].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Benzamide-d5 相关抗体:
分子量

126.17

Formula

C7H2D5NO
CAS 号
非标记 CAS
中文名称

苯甲酰胺-d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Benzamide-d5 相关分类

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Keywords:

Benzamide-d51235489-47-0Benzenecarboxamide-d5 Phenylamide-d5苯甲酰胺-d5PARPIsotope-Labeled CompoundsEndogenous Metabolitepoly ADP ribose polymeraseInhibitorinhibitorinhibit

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