1. Immunology/Inflammation
  2. Interleukin Related
  3. Brodalumab

Brodalumab  (Synonyms: AMG 827; KHK4827)

目录号: HY-P9925 纯度: 97.23%
COA

Brodalumab (AMG 827) 是一种抗人白介素 17 受体 (IL-17R) IgG2 单克隆抗体,可用于研究中重度斑块性银屑病和类风湿性关节炎。

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Brodalumab Chemical Structure

Brodalumab Chemical Structure

CAS No. : 1174395-19-7

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规格 价格 是否有货 数量
1 mg ¥1500
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5 mg ¥4800
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10 mg ¥7440
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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis[1][2].

IC50 & Target

IL-17R[1]

体外研究
(In Vitro)

Brodalumab (AMG 827) 通过 IL-17RA/RC 复合物阻断 IL-17A、IL-17F 和 IL17-A/F 异源二聚体信号通路的生物活性,以及通过 IL-17RA/RB 复合物阻断 IL-25 (IL-17E) 信号通路的生物活性[2]
Brodalumab 能够抑制银屑病的炎症过程[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Brodalumab
目录号:
HY-P9925
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