1. Cell Cycle/DNA Damage
  2. CDK
  3. CDK9-IN-26

CDK9-IN-26 (compound 1d) 是 CDK9 抑制剂 (IC50=0.18 μM)。

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CDK9-IN-26

CDK9-IN-26 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CDK9-IN-26 (compound 1is a CDK9 inhibitor (IC50=0.18 μM). [1].

IC50 & Target

IC50: 0.18 μM (CDK9)[1]

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HCT-116 IC50
11.62 μM
Compound: 63; Cpd 1d
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
[PMID: 38564299]
K562 IC50
11.62 μM
Compound: 63; Cpd 1d
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
Antiproliferative activity against human K562 cells assessed as reduction in cell viability incubated for 72 hrs by CCK-8 assay
[PMID: 38564299]
MCF7 IC50
11.62 μM
Compound: 63; Cpd 1d
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
[PMID: 38564299]
分子量

306.32

Formula

C17H14N4O2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
CDK9-IN-26
目录号:
HY-155844
需求量: