2. GPCR/G Protein Neuronal Signaling Cytoskeleton NF-κB Metabolic Enzyme/Protease Immunology/Inflammation Apoptosis
  3. GPR55 Collagen Reactive Oxygen Species (ROS) Apoptosis
  4. Cyclic peptide P1-1

Cyclic peptide P1-1 是一种高效的 GPR55 拮抗剂。Cyclic peptide P1-1 拮抗 GPR55 并抑制 collagen 分泌。Cyclic peptide P1-1 减少 ROS 的产生，减轻内质网应激，并抑制线粒体相关的凋亡 (Apoptosis)。Cyclic peptide P1-1 抑制 α-SMA 和 COL1α 的表达。Cyclic peptide P1-1 可改善 CCl4 (HY-Y0298) 和 MCD 饮食诱导的急性肝脏炎症和纤维化。

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Custom Peptide Synthesis

Cyclic peptide P1-1

Cyclic peptide P1-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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Customer Review

Cyclic peptide P1-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclic peptide P1-1 is a high-potent GPR55 antagonist. Cyclic peptide P1-1 antagonizes GPR55 and suppresses collagen secretion. Cyclic peptide P1-1 reduces ROS production, attenuates ER stress, and inhibits mitochondria-associated Apoptosis. Cyclic peptide P1-1 inhibits the expression of α-SMA and COL1α. Cyclic peptide P1-1 ameliorates CCl4 (HY-Y0298)-induce and MCD-diet-induce acute liver inflammation and fibrosis[1].

分子量

991.19

Formula

C40H70N12O13S2
Sequence

Cys-Lys-Lys-Asn-Ser-Pro-Thr-Ile-Cys (Disulfide bridge: Cys1-Cys9)
Sequence Shortening

CKKNSPTIC (Disulfide bridge: Cys1-Cys9)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cyclic peptide P1-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclic peptide P1-1GPR55CollagenReactive Oxygen Species (ROS)ApoptosisG protein-coupled receptor 55Inhibitorinhibitorinhibit

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目录号：
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