2. Immunology/Inflammation
  3. Interleukin Related
  4. Elsilimomab

Elsilimomab  (Synonyms: B-E8; Anti-IL-6 MAB B-E8; Anti-Human IL6 Recombinant Antibody)

目录号: HY-P99287 纯度: 95.00%
COA

摩尔计算器

Elsilimomab (B-E8) 是一种抗白介素-6 (IL-6) 的 IgG1 单克隆抗体，其 KD 为 22 pM，IC50 为 1.4 nM。Elsilimomab 可用于多发性骨髓瘤、肾细胞癌和类风湿性关节炎 (RA) 的研究。

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Elsilimomab Chemical Structure

Elsilimomab Chemical Structure

CAS No. : 468715-71-1

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规格 价格 是否有货 数量
1 mg ￥4000
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Elsilimomab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6), with a KD of 22 pM and an IC50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA)[1][2][3].

IC50 & Target

IL-6

1.4 nM (IC50)

体外研究
(In Vitro)

Elsilimomab 特异性抑制 IL-6，但不抑制 LIF (白血病抑制因子)诱导的细胞生长[2]。
Elsilimomab (20 μg/mL) 可中和人 IL-6[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Elsilimomab 相关抗体:

Cell Viability Assay[2]

Cell Line: Murine B9 cells
Concentration: 20 μg/mL
Incubation Time: 3 days
Result: B9 cells were stimulated with human IL-6, which was effectively neutralized by antibody Elsilimomab.
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Elsilimomab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Elsilimomab468715-71-1B-E8 Anti-IL-6 MAB B-E8 Anti-Human IL6 Recombinant AntibodyInterleukin RelatedILMurine B9 cellsmonoclonal antibodymultiple myelomarenal cell carcinomarheumatoid arthritisInhibitorinhibitorinhibit

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