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  2. PDAP1 - PDGFA associated protein 1 Gene

PDAP1 - PDGFA associated protein 1 Gene

中文名称:PDGFA 相关蛋白 1

种属: Homo sapiens

同用名: PAP; PAP1; HASPP28

基因 ID: 11333 | 基因类型: protein coding

关于 PDAP1

Cytogenetic location: 7q22.1 Genomic coordinates (GRCh38): 7:99,394,673-99,408,597 (from NCBI)

This gene has 5 transcripts (splice variants) and 187 orthologues. Ubiquitous expression in fat (RPKM 24.9), colon (RPKM 23.3) and 25 other tissues.

功能概要

该基因编码的蛋白质是一种磷蛋白,可上调 PDGFA 刺激的成纤维细胞生长,并下调 PDGFB 的促有丝分裂性。啮齿动物中编码的蛋白质已显示以低亲和力结合 PDGFA。[RefSeq 提供,2010 年 12 月]

The protein encoded by this gene is a phosphoprotein that may upregulate the PDGFA-stimulated growth of fibroblasts and also downregulate the mitogenicity of PDGFB. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. [provided by RefSeq, Dec 2010]

PDAP1 基因产物(1)

mRNA Protein Name
NM_014891.7 NP_055706.1 28 kDa heat- and acid-stable phosphoprotein

PDAP1 蛋白结构

PP28

PP28: Casein kinase substrate phosphoprotein PP28 (84 - 164)

  • 0
  • 100
  • 181 a.a.
蛋白主名 其他名称

28 kDa heat- and acid-stable phosphoprotein

PDGF-associated protein

重组 PDAP1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71186 PAP Protein, Human (His) Q13442 (M1-K181) ≥95%

直系同源

种属 基因名 来源 基因 ID
Bos taurus PDAP1 VGNC VGNC:32655
Felis catus PDAP1 VGNC VGNC:64076
Canis familiaris PDAP1 VGNC VGNC:44332
Rattus norvegicus PDAP1 RGD RGD:620442
Macaca mulatta PDAP1 VGNC VGNC:75604
Mus musculus PDAP1 MGD MGI:2448536
Others PDAP1 NCBI