1. Gene
  2. Cdk6 - cyclin-dependent kinase 6 Gene

Cdk6 - cyclin-dependent kinase 6 Gene

中文名称:细胞周期蛋白依赖性激酶 6

种属: Mus musculus

同用名: Crk2

基因 ID: 12571 | 基因类型: protein coding

关于 Cdk6

Chromosome 5: 3,391,485-3,581,008 forward strand.GRCm39:CM000998.3

This gene has 6 transcripts (splice variants), 199 orthologues, 25 paralogues and is associated with 48 phenotypes. Ubiquitous expression in thymus adult (RPKM 7.), lung adult (RPKM 3.6) and 26 other tissues.


该基因编码细胞周期蛋白依赖性激酶蛋白家族的成员,该蛋白在细胞周期的进程和调节中起着重要作用。编码的蛋白质与 D 型细胞周期蛋白结合形成活性激酶复合物,以调节细胞周期 G1 期的进程。缺乏编码蛋白的小鼠表现出胸腺和脾脏发育不全,以及造血缺陷,例如巨核细胞和红细胞数量减少。该基因的假基因已在 4 号染色体上定义。[RefSeq 提供,2015 年 8 月]

This gene encodes a member of the cyclin dependent kinase family of proteins that play important roles in the progression and regulation of the cell cycle. The encoded protein binds to a D-type cyclin to form an active kinase complex to regulate progression through the G1 phase of the cell cycle. Mice lacking the encoded protein exhibit thymic and splenic hypoplasia, and hematopoietic defects such as reduced number of megakaryocytes and erythrocytes. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2015]

Cdk6 基因产物(1)

mRNA Protein Name
NM_009873.3 NP_034003.1 cyclin-dependent kinase 6

Cdk6 蛋白结构


STKc_CDK6: cd07862 (10 - 299)

  • 0
  • 100
  • 200
  • 300
  • 326 a.a.
蛋白主名 其他名称

cyclin-dependent kinase 6

CR2 protein kinase

cell division protein kinase 6

serine/threonine-protein kinase PLSTIRE


种属 基因名 来源 基因 ID
Homo sapiens Cdk6 NCBI NCBI:1021