1. Gene
  2. NRG4 - neuregulin 4 Gene

NRG4 - neuregulin 4 Gene

中文名称:神经调节蛋白 4

种属: Homo sapiens

同用名: HRG4

基因 ID: 145957 | 基因类型: protein coding

关于 NRG4

Cytogenetic location: 15q24.2 Genomic coordinates (GRCh38): 15:75,935,393-76,060,240 (from NCBI)

This gene has 16 transcripts (splice variants), 103 orthologues and 3 paralogues. Ubiquitous expression in prostate (RPKM 2.0), skin (RPKM 1.9) and 25 other tissues.

功能概要

神经调节蛋白,包括 NRG4,激活 1 型生长因子受体 (参见 EGFR;MIM 131550) 以通过酪氨酸磷酸化启动细胞间信号传导 (Harari 等人,1999 [PubMed 10348342]) 。[OMIM 提供,3 月 2008]

The Neuregulins, including NRG4, activate type-1 growth factor receptors (see EGFR; MIM 131550) to initiating cell-to-cell signaling through tyrosine phosphorylation (Harari et al., 1999 [PubMed 10348342]).[supplied by OMIM, Mar 2008]

NRG4 基因产物(1)

mRNA Protein Name
NM_138573.4 NP_612640.1 pro-neuregulin-4, membrane-bound isoform
蛋白主名 其他名称

pro-neuregulin-4, membrane-bound isoform

heregulin 4

重组 NRG4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76524 Neuregulin-4/NRG4 Protein, Human Q8WWG1 (GP&P2-F62) ≥95%

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta NRG4 VGNC VGNC:84411
Rattus norvegicus NRG4 RGD RGD:1589860
Felis catus NRG4 VGNC VGNC:80904
Mus musculus NRG4 MGD MGI:1933833
Others NRG4 NCBI