2. Gene
  3. PLA2G4D - phospholipase A2 group IVD Gene

PLA2G4D - phospholipase A2 group IVD Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：磷脂酶 A2 组 IVD

种属: Homo sapiens

同用名: cPLA2delta

基因 ID: 283748 | 基因类型: protein coding

关于 PLA2G4D

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:42,067,009-42,094,562 (from NCBI)

This gene has 3 transcripts (splice variants), 140 orthologues and 5 paralogues. Biased expression in skin (RPKM 6.8), prostate (RPKM 6.7) and 2 other tissues.

功能概要

磷脂酶 A2 酶家族，包括 PLA2G4D，在 sn-2 位催化甘油磷脂水解，然后释放游离脂肪酸和溶血磷脂 (Chiba 等人，2004 [PubMed 14709560]) 。[OMIM 提供，2009 年 6 月]

The Phospholipase A2 Enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2 position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 [PubMed 14709560]).[supplied by OMIM, Jun 2009]

PLA2G4D 基因产物(1)

mRNA Protein Name
NM_178034.4 NP_828848.3 cytosolic phospholipase A2 delta

PLA2G4D 蛋白结构

C2

C2: C2 domain (24 - 104)

PLA2_B

PLA2_B: Lysophospholipase catalytic domain (323 - 514)

  • 0
  • 200
  • 400
  • 600
  • 818 a.a.
蛋白主名 其他名称

cytosolic phospholipase A2 delta

cPLA2-delta

关联疾病

疾病名称 别名
Dyskeratosis Congenita, Autosomal Recessive 2

DKCB2

Autosomal Recessive Dyskeratosis Congenita 2

Dyskeratosis Congenita, Autosomal Recessive, 2

Dyskeratosis Congenita, Autosomal Recessive, Type 2
Immunodeficiency 29

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Il12b Deficiency

IMD29

Il12b Deficiency

Immunodeficiency 29, Mycobacteriosis

Mendelian Susceptibility To Mycobacterial Diseases Due To Complete Interleukin 12b Deficiency

Msmd Due To Complete Il12b Deficiency

Msmd Due To Complete Interleukin 12b Deficiency

Immunodeficiency, Type 29, Mycobacteriosis
Oliver-Mcfarlane Syndrome

Trichomegaly-Retina Pigmentary Degeneration-Dwarfism Syndrome

OMCS

Long Eyelashes-Intellectual Disability Syndrome

Trichomegaly With Mental Retardation, Dwarfism, And Pigmentary Degeneration Of Retina

Eyelashes, Long, With Mental Retardation

Eyelashes Long Mental Retardation

Trichomegaly With Intellectual Disability, Dwarfism And Pigmentary Degeneration

Trichomegaly With Intellectual Disability, Dwarfism And Pigmentary Degeneration Of Retina

Eyelashes, Long With Intellectual Disability

Oliver Mcfarlane Syndrome

Congenital Trichomegaly, Pigmentary Retinal Degeneration, And Short Stature

Trichomegaly, Retina Pigmentary Degeneration, Dwarfism

Trichomegaly Retina Pigmentary Degeneration Dwarfism
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10629 PLA2G4D Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris PLA2G4D VGNC VGNC:44627
Bos taurus PLA2G4D VGNC VGNC:32961
Felis catus PLA2G4D VGNC VGNC:64200
Mus musculus PLA2G4D MGD MGI:1925640
Macaca mulatta PLA2G4D VGNC VGNC:76136
Rattus norvegicus PLA2G4D RGD RGD:1593372
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