2. Gene
  3. UBE2T - ubiquitin conjugating enzyme E2 T Gene

UBE2T - ubiquitin conjugating enzyme E2 T Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：泛素结合酶 E2 T

种属: Homo sapiens

同用名: FANCT; PIG50; HSPC150

基因 ID: 29089 | 基因类型: protein coding

关于 UBE2T

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:202,331,657-202,341,936 (from NCBI)

This gene has 12 transcripts (splice variants), 196 orthologues, 24 paralogues and is associated with 3 phenotypes. Broad expression in testis (RPKM 10.4), bone marrow (RPKM 10.2) and 22 other tissues.

功能概要

由该基因编码的蛋白质催化泛素与蛋白质底物的共价结合。该基因的缺陷与互补组 T 的 Fanconi 贫血有关。已发现该基因编码不同亚型的两种转录变体。[RefSeq 提供，2015 年 7 月]

The protein encoded by this gene catalyzes the covalent attachment of ubiquitin to protein substrates. Defects in this gene have been associated with Fanconi anemia of complementation group T. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015]

UBE2T 基因产物(2)

mRNA Protein Name
NM_001310326.2 NP_001297255.1 ubiquitin-conjugating enzyme E2 T isoform 2
NM_014176.4 NP_054895.1 ubiquitin-conjugating enzyme E2 T isoform 1

UBE2T 蛋白结构

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (6 - 146)

  • 0
  • 100
  • 197 a.a.
蛋白主名 其他名称

ubiquitin-conjugating enzyme E2 T

E2 ubiquitin-conjugating enzyme T

重组 UBE2T 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71409 UBE2T Protein, Human (His) Q9NPD8 (M1-V197) ≥95%

关联疾病

疾病名称 别名
Fanconi Anemia, Complementation Group T

Fanconi Anemia Complementation Group T

FANCT
Fanconi Anemia, Complementation Group A

Fanconi Anemia

Fanconi Pancytopenia

Fanconi Anemia Complementation Group A

FANCA

Fa

Fanconi Panmyelopathy

Fanconi'S Anemia

Fanconi Anaemia

Fanconi'S Anaemia

Fanconi Hypoplastic Anemia

Estren-Dameshek Variant Of Fanconi Anemia

Estren-Dameshek Variant Of Fanconi Pancytopenia

Fanconi Anemia Estren-Dameshek Variant

Fanconis Anemia
Fanconi Anemia, Complementation Group R

Fanconi Anemia Complementation Group R

FANCR
Fanconi Anemia, Complementation Group Q

Fanconi Anemia Complementation Group Q

FANCQ
Fanconi Anemia, Complementation Group I

Fanconi Anemia Complementation Group I

FANCI
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
Fanconi Anemia, Complementation Group D2

Fanconi Anemia Complementation Group D2

FANCD2

Fad2

Fa4

Fancd

Fanconi Pancytopenia Type 4

Fanconi Anemia, Complementation Group D

Fanconi Pancytopenia, Type 4

Facd

Fanconi Anemia Complementation Group D
Aplastic Anemia

Aplastic Anemia, Susceptibility To

Anemia Aplastic

Idiopathic Aplastic Anemia

Secondary Aplastic Anemia

Idiopathic Bone Marrow Failure

Aplastic Anemia Idiopathic

AA

Anemia, Aplastic

Aplastic Anemia, Idiopathic

Erythroid Aplasia

Aa - [Aplastic Anaemia]

Haematopoietic Aplasia

Aleukia Haemorrhagica

Anaemia Due To Decreased Red Cell Production

Aplasia Bone Marrow

Aplastic Bone Marrow

Hypoplastic Anaemia Nos

Myeloid Bone Marrow Aplasia

Pancytopenia

Panhaematopenia

Hypoproliferative Anaemia

Medullary Hypoplasia

Red Blood Cells Hypoplastic Anaemia

Panmyelophthisis

Panhemocytopenia

Refractive Hypoproliferative Anaemia

Toxic Anaemia

Toxic Aplastic Anaemia

Aplastic Anaemia Due To Toxic Cause

Idiopathic Aplastic Anaemia Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-141891 M435-1279 Inhibitor 98.43% 否
HY-126539 UBE2T/FANCL-IN-1 99.83% 否
HY-RS15362 UBE2T Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus UBE2T VGNC VGNC:36596
Macaca mulatta UBE2T VGNC VGNC:79467
Felis catus UBE2T VGNC VGNC:66765
Mus musculus UBE2T MGD MGI:1914446
Canis familiaris UBE2T VGNC VGNC:48066
Rattus norvegicus UBE2T RGD RGD:1310816
Others UBE2T NCBI
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