2. Gene
  3. IGHG2 - immunoglobulin heavy constant gamma 2 (G2m marker) Gene

IGHG2 - immunoglobulin heavy constant gamma 2 (G2m marker) Gene

  • 基因
  • 蛋白
  • 疾病
  • 直系同源

中文名称：免疫球蛋白重常数伽马 2 (G2m 标记)

种属: Homo sapiens

基因 ID: 3501 | 基因类型: other

关于 IGHG2

Cytogenetic location: 14q32.33 Genomic coordinates (GRCh38): 14:105,643,203-105,644,789 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 121 orthologues, 82 paralogues and is associated with 1 phenotype.

功能概要

预测启用抗原结合活性和免疫球蛋白受体结合活性。预计参与多个过程，包括激活免疫反应；对其他生物体的防御反应；和吞噬作用。位于细胞外空间。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

IGHG2 蛋白结构

C1-set

C1-set: Immunoglobulin C1-set domain (17 - 92)

C1-set

C1-set: Immunoglobulin C1-set domain (126 - 212)

C1-set

C1-set: Immunoglobulin C1-set domain (232 - 314)

  • 0
  • 100
  • 200
  • 300
  • 326 a.a.

重组 IGHG2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72601 IgG2 Fc Protein, Human (223a.a, V161M, S257A, HEK293) P01859 (V104-K326) ≥95%
HY-P72605 IgG2 Fc Protein, Human (228a.a, V161M, S257A, HEK293) P01859 (E99-K326, V161M, S257A) ≥95%
HY-P73144 IgG2 Fc Protein, Human (229a.a, S257A, HEK293) P01859 (E99-K327, S257A) ≥95%

关联疾病

疾病名称 别名
Immunoglobulin Kappa Light Chain Deficiency

Recurrent Infections Associated With Rare Immunoglobulin Isotypes Deficiency

IGKCD

Kappa Chain Deficiency

Kappa Light Chain Deficiency

Kappa-Chain Deficiency

Igg Subclass Deficiency With Iga Subclass Deficiency

Isolated Igg Subclass Deficiency

Selective Igg Subclass Deficiency
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus IGHG2 NCBI
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