CYP3A43 - cytochrome P450 family 3 subfamily A member 43 Gene

中文名称：细胞色素 P450 家族 3 亚家族 A 成员 43

种属: Homo sapiens

关于 CYP3A43

功能概要

该基因编码细胞色素 P450 酶超家族的成员。细胞色素 P450 蛋白是单加氧酶，可催化许多涉及药物代谢和胆固醇、类固醇和其他脂质合成的反应。编码的蛋白质具有低水平的睾酮羟化酶活性，可能在衰老机制和癌症进展中发挥作用。该基因是染色体 7q21.1 上细胞色素 P450 基因簇的一部分。交替剪接导致编码不同异构体的多个转录变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and Cancer progression. This gene is part of a cluster of Cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]