1. Apoptosis
  2. Apoptosis
  3. Kauran-16,17-diol

Kauran-16,17-diol  (Synonyms: ent-Kauran-16β,17-diol)

目录号: HY-N7422 纯度: 99.51%
COA 产品使用指南

Kauran-16,17-diol (ent-Kauran-16β,17-diol) 是一个天然的二萜化合物,具有抗肿瘤诱导凋亡的活性。其抑制 LPS 诱导的RAW 264.7 细胞产生 NO 的 IC50 值为17 μM。

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Kauran-16,17-diol Chemical Structure

Kauran-16,17-diol Chemical Structure

CAS No. : 16836-31-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].

体外研究
(In Vitro)

Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

306.48

Formula

C20H34O2

CAS 号
性状

固体

颜色

White to off-white

中文名称

对映-贝壳杉-16β,17-二醇

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Kauran-16,17-diol 相关分类

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  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Kauran-16,17-diol
目录号:
HY-N7422
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