1. Apoptosis
  2. Apoptosis
  3. Kauran-16,17-diol

Kauran-16,17-diol (Synonyms: ent-Kauran-16β,17-diol)

目录号: HY-N7422
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Kauran-16,17-diol (ent-Kauran-16β,17-diol) 是一个天然的二萜化合物,具有抗肿瘤诱导凋亡的活性。其抑制 LPS 诱导的RAW 264.7 细胞产生 NO 的 IC50 值为17 μM。

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Kauran-16,17-diol Chemical Structure

Kauran-16,17-diol Chemical Structure

CAS No. : 16836-31-0

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Description

Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].

In Vitro

Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells[1].

Molecular Weight

306.48

Formula

C₂₀H₃₄O₂

CAS No.

16836-31-0

中文名称

对映-贝壳杉-16β,17-二醇

SMILES

C[C@]1(CCC2)[C@@]3([H])[C@](C[C@H]4CC3)(CC[C@]1([H])C2(C)C)C[C@]4(O)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Kauran-16,17-diolent-Kauran-16β,17-diolApoptosisInhibitorinhibitorinhibit

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产品名称:
Kauran-16,17-diol
目录号:
HY-N7422
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