2. PROTAC Protein Tyrosine Kinase/RTK
  3. Molecular Glues Src
  4. Lck degrader-1

Lck degrader-1 (Compound 17) 是一种分子胶 (molecular glue) 降解剂，靶向淋巴细胞特异性蛋白酪氨酸激酶 (LCK) (DC50=23.1 nM)。Lck degrader-1 有望用于 T 细胞急性淋巴细胞白血病 (T-ALL) 的研究。

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Lck degrader-1

Lck degrader-1 Chemical Structure

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Lck degrader-1 相关抗体

Top Publications Citing Use of Products

查看 Src 亚型特异性产品:

查看所有亚型
Lck Fyn Blk Hck Lyn Yes SRC-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lck degrader-1 (Compound 17) is a molecular glue degrader targeting lymphocyte-specific protein tyrosine kinase (LCK) (DC50=23.1 nM). Lck degrader-1 is promising for research of T-cell acute lymphoblastic leukemia (T-ALL)[1].

分子量

459.50

Formula

C25H25N5O4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lck degrader-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lck degrader-1Lck degrader1Lck degrader 1Molecular GluesSrcmolecular glueLCKT-ALLInhibitorinhibitorinhibit

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产品名称：
Lck degrader-1
目录号：
HY-175280
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