1. Metabolic Enzyme/Protease
  2. Mitochondrial Metabolism
  3. Ligustroside

Ligustroside  (Synonyms: Ligstroside)

目录号: HY-N3383 纯度: ≥98.0%
COA 产品使用指南

Ligustroside (Ligstroside) 是一种 secoiridoid 衍生物,在早期阿尔茨海默病 (AD) 和脑老化模型中的线粒体生物能量学方面表现出色,其机制可能不会干扰 Aβ 的产生。Ligustroside 显着抑制脂多糖激活的 RAW264.7 巨噬细胞中一氧化氮的产生。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

Ligustroside Chemical Structure

Ligustroside Chemical Structure

CAS No. : 35897-92-8

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥2500
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Ligustroside (Ligstroside), a secoiridoid derivative, has outstanding performance on mitochondrial bioenergetics in models of early Alzheimer's disease (AD) and brain ageing by mechanisms that may not interfere with Aβ production. Ligustroside significantly inhibits nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages[1][2].

体外研究
(In Vitro)

Ligstroside increases mRNA expression of SIRT1, CREB1, complex I, and GPx1 in SH-SY5Y-APP695 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Ligstroside (50 mg/kg; a supplemented diet for 6 months) protects against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Female NMRI mice, aged 12 months[1]
Dosage: 50 mg/kg
Administration: Received a supplemented diet for 6 months (equivalent to 6.25 mg/kg b.w.)
Result: Showed improved spatial working memory; Restored brain ATP levels in aged mice and led to a significant life extension compared to aged control animals.
分子量

524.51

Formula

C25H32O12

CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

纯度: ≥98.0%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Ligustroside
目录号:
HY-N3383
需求量: