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  2. Ligands for Target Protein for PROTAC
  3. N-Deshydroxyethyl Dasatinib-d8

N-Deshydroxyethyl Dasatinib-d8 

目录号: HY-107447S
产品使用指南

N-Deshydroxyethyl Dasatinib-d8 是 N-Deshydroxyethyl Dasatinib 的氘代物。N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825) 是一种基于 Dasatinib (ABL 抑制剂) 的配体,可通过 linker 与 IAP 配体结合从而形成 SNIPER 分子,从而降解 ABL。

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N-Deshydroxyethyl Dasatinib-d8 Chemical Structure

N-Deshydroxyethyl Dasatinib-d8 Chemical Structure

CAS No. : 1189998-96-6

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生物活性

N-Deshydroxyethyl Dasatinib-d8 is the deuterium labeled N-Deshydroxyethyl Dasatinib. N-Deshydroxyethyl Dasatinib (N-Deshydroxyethyl BMS-354825), the Dasatinib-based moiety, binds to IAP ligand via a linker to form SNIPER to degrade ABL[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

452.00

Formula

C20H14D8ClN7OS

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
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产品名称:
N-Deshydroxyethyl Dasatinib-d8
目录号:
HY-107447S
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