1. Others Neuronal Signaling GPCR/G Protein
  2. Dopamine Receptor 5-HT Receptor Isotope-Labeled Compounds
  3. Paliperidone palmitate-d4

Paliperidone palmitate-d4  (Synonyms: 9-Hydroxyrisperidone palmitate-d4)

目录号: HY-A0019AS
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Paliperidone palmitate-d4 (9-Hydroxyrisperidone palmitate-d4) 是 Paliperidone palmitate (HY-A0019A) 的氘代物。Paliperidone palmitate 是一种口服有效、可以通过血脑屏障的多巴胺 D2 受体和 5-羟色胺 2A (5-HT2A) 受体的竞争性拮抗剂。Paliperidone palmitate 通过与多巴胺 D2 受体和 5-HT2A 受体结合,竞争性地抑制多巴胺和 5-羟色胺的作用,调节神经递质系统的平衡,从而发挥抗精神病活性。Paliperidone palmitate 主要用于精神分裂症的研究。

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Paliperidone palmitate-d<sub>4</sub>

Paliperidone palmitate-d4 Chemical Structure

CAS No. : 1794685-21-4

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  • 生物活性

  • 纯度 & 产品资料

生物活性

Paliperidone palmitate-d4 (9-Hydroxyrisperidone palmitate-d4) is the deuterium labeled Paliperidone palmitate (HY-A0019A). Paliperidone palmitate is an orally effective competitive antagonist of dopamine D2 receptors and 5-hydroxytryptamine 2A (5-HT2A) receptors that can cross the blood-brain barrier. Paliperidone palmitate competitively inhibits the effects of dopamine and 5-hydroxytryptamine by binding to dopamine D2 receptors and 5-HT2A receptors, regulating the balance of the neurotransmitter system and thus exerting antipsychotic activity. Paliperidone palmitate is mainly used in the research field of schizophrenia[1][2][3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被掺入药物分子中,主要用作药物开发过程中定量的示踪剂。氘化因其可能影响药物的药代动力学和代谢特征而受到关注。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

668.92

Formula

C39H53D4FN4O4

CAS 号
非标记 CAS
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Paliperidone palmitate-d4
目录号:
HY-A0019AS
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