1. Saccharides and Glycosides
  2. Prosaikogenin G

Prosaikogenin G 

目录号: HY-N7665
产品使用指南

Prosaikogenin G 是从柴胡的根中分离出的,对 Ang II 诱导的大鼠系膜细胞增殖具有明显的抑制作用。Prosaikogenin G 对肾脏有保护作用。Prosaikogenin G 是 Saikosaponin d 在胃肠道中的衍生物。

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Prosaikogenin G Chemical Structure

Prosaikogenin G Chemical Structure

CAS No. : 99365-23-8

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Description

Prosaikogenin G, isolated from the roots of Buleurum bicaule Helm (Apiaceae), exhibits significant inhibitory effects on rat mesangial cell proliferation induced by Ang II. Prosaikogenin G has protective action on the kidney[1]. Prosaikogenin G is a derivative of Saikosaponin d in the gastrointestinal tract[2].

In Vitro

Prosaikogenin G (25, 50 μM) has protective action on the kidney for their down-regulated activity to the rat mesangial cell line (MC) proliferation induced by Ang II (1 μM), and does not exhibit injury to the normal MC[1].

Molecular Weight

618.84

Formula

C₃₆H₅₈O₈

CAS No.

99365-23-8

中文名称

柴胡次皂苷G

SMILES

O[C@H]([C@H]([C@H]([C@@H](C)O1)O)O)[C@@H]1O[C@@H]2CC[C@]3(C)[C@@]4([H])C=C[C@]56[C@]7([H])CC(C)(C)CC[C@@](CO6)7[C@@H](O)C[C@](C)5[C@@](C)4CC[C@]([H])3[C@@]2(C)CO

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Prosaikogenin GOthersInhibitorinhibitorinhibit

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目录号:
HY-N7665
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