2. Anti-infection Membrane Transporter/Ion Channel
  3. Parasite Potassium Channel
  4. Quinine hemisulfate hydrate

Quinine hemisulfate hydrate  (Synonyms: 硫酸奎宁水合物)

目录号: HY-D0143B
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Quinine hemisulfate hydrate 是一种从金鸡纳树皮中提取的生物碱，具有抗疟疾的作用。Quinine hemisulfate hydrate 是一种钾离子通道 (potassium channel) 抑制剂，可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其 IC50 值为 169 μM。

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Quinine hemisulfate hydrate Chemical Structure

Quinine hemisulfate hydrate Chemical Structure

CAS No. : 207671-44-1

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Other Forms of Quinine hemisulfate hydrate:

Quinine hemisulfate hydrate 相关抗体

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生物活性

Quinine hemisulfate hydrate, an alkaloid derived from the bark of the cinchona tree, acts as an anti-malaria agent. Quinine hemisulfate hydrate is a potassium channel inhibitor that inhibits WT mouse Slo3 (KCa5.1) channel currents evoked by voltage pulses to +100 mV, with an IC50 of 169 μM[1][2].

IC50 & Target

IC50: Parasite[1], 169 μM (mSlo3)[2]
Clinical Trial
分子量

391.48

Formula

C20H24N2O2.1/2H2O4S.H2O
CAS 号
中文名称

硫酸奎宁水合物
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Quinine hemisulfate hydrate 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Quinine hemisulfate207671-44-1硫酸奎宁水合物ParasitePotassium ChannelKcsAanti-malariaparasitepotassiumchannelKCa5.1Slo3Inhibitorinhibitorinhibit

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