1. Neuronal Signaling GPCR/G Protein
  2. 5-HT Receptor Serotonin Transporter
  3. (R)-Citalopram oxalate

(R)-Citalopram oxalate  (Synonyms: (R)-草酸西酞普兰)

目录号: HY-110289
产品使用指南

(R)-Citalopram oxalate 是一种抗惊厥药、抗抑郁药和肌肉松弛药。(R)-Citalopram oxalate 作为 5-HT 转运蛋白 (SERT) 抑制剂的作用比 S-citalopram (Escitalopram; HY-14258) 至少弱 20 倍。(R)-Citalopram oxalate 在体内和体外功能性拮抗 S-citalopram。(R)-Citalopram oxalate 通过变构机制影响 Escitalopram 与高亲和力初级位点的结合,并影响其与 5-HT 转运蛋白的解离。

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(R)-Citalopram oxalate Chemical Structure

(R)-Citalopram oxalate Chemical Structure

CAS No. : 219861-53-7

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  • 参考文献

生物活性

(R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram; HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism[1].

分子量

414.43

Formula

C22H23FN2O5

CAS 号
中文名称

(R)-草酸西酞普兰

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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产品名称:
(R)-Citalopram oxalate
目录号:
HY-110289
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