CD20 蛋白, Human (Trx)

CD20/MS4A1 Protein, a B-lymphocyte membrane protein, crucially regulates cellular calcium influx, essential for B-lymphocyte development, differentiation, and activation. As part of the store-operated calcium (SOC) channel, it promotes calcium influx upon B-cell receptor/BCR activation. CD20/MS4A1 forms homotetramers, contributing to its structural organization in calcium signaling. Interacting with both heavy and light chains of cell surface IgM, the antigen-binding components of the BCR, emphasizes its involvement in the B-cell receptor complex, underscoring significance in B-cell activation and immune responses. CD20 Protein, Human (Trx) is the recombinant human-derived CD20 protein, expressed by E. coli, with N-Trx labeled tag. The total length of CD20 Protein, Human (Trx) is 48 a.a., with molecular weight of 28.2 kDa.

CD20/MS4A1 蛋白是一种 B 淋巴细胞特异性膜蛋白，在调节细胞钙内流方面发挥着至关重要的作用，而钙内流对于 B 淋巴细胞的发育、分化和激活至关重要。它作为钙库操纵 (SOC) 通道的组成部分发挥作用，在 B 细胞受体/BCR 激活后促进钙流入。CD20/MS4A1 形成同源四聚体，有助于其结构组织和在钙信号传导中的功能作用。值得注意的是，它与细胞表面 IgM 的重链和轻链（BCR 的抗原结合成分）相互作用，突出了它在 B 细胞受体复合物中的参与，并强调了它在 B 细胞激活和免疫反应中的重要性。

Human

E. coli

N-Trx

P11836/NP_068769.2 (I141-S188)

931  [NCBI]

IKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQS

28.2 kDa

Greater than 80% as determined by reducing SDS-PAGE.