Serpin E2 蛋白, Mouse (HEK293, His, solution)

Serpin E2, a serine protease inhibitor, inhibits thrombin, trypsin, and urokinase, with a notable role in promoting neurite extension by specifically inhibiting thrombin. Its ability to bind heparin underscores interactions with glycosaminoglycans. The multifaceted inhibitory functions of Serpin E2 highlight its significance in regulating serine protease activities and potential impact on cellular processes, particularly in neurodevelopment. Serpin E2 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Serpin E2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Serpin E2 Protein, Mouse (HEK293, His, solution) is 378 a.a., with molecular weight of approximately 48 kDa.

Serpin E2 是一种丝氨酸蛋白酶抑制剂，对凝血酶、胰蛋白酶和尿激酶具有抑制活性。值得注意的是，它通过特异性抑制凝血酶来促进神经突延伸，强调其参与神经发育过程。此外，丝氨酸蛋白酶抑制剂 E2 因其结合肝素的能力而被认可，展示了它与这种重要的糖胺聚糖的相互作用。Serpin E2 的多方面抑制功能强调了其在调节丝氨酸蛋白酶活性方面的重要性及其对细胞过程的潜在影响，特别是在神经发育的背景下。

Mouse

HEK293

C-10*His

Q07235 (S20-P397)

20720  [NCBI]

SQFNSLSLEELGSNTGIQVFNQIIKSRPHENVVVSPHGIASILGMLQLGADGKTKKQLSTVMRYNVNGVGKVLKKINKAIVSKKNKDIVTVANAVFLRNGFKMEVPFAVRNKDVFQCEVQNVNFQDPASASESINFWVKNETRGMIDNLLSPNLIDGALTRLVLVNAVYFKGLWKSRFQPESTKKRTFVAGDGKSYQVPMLAQLSVFRSGSTRTPNGLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHITTKTIDSWMNTMVPKRMQLVLPKFTAVAQTDLKEPLKALGITEMFEPSKANFTKITRSESLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFSIRHNPTGAILFLGQVNKP

approximately 48 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.